Can You Overdose on Flexeril? Side Effects & Symptoms

Always discuss possible side effects with a healthcare professional who knows your medical history. If you experience severe skin rash, swelling of the face or tongue, difficulty breathing or swallowing, irregular heart rate, chest pain, fever or seizures, the NIH recommends contacting a doctor immediately. These side effects, which have been reported in other similar tricyclic antidepressants to the FDA, could be indications of arrhythmias, sinus tachycardia, leading to myocardial infarction and stroke. Some common side effects include drowsiness, dry mouth, dizziness, fatigue or upset stomach. If these side effects become severe or cause problems in your everyday life, the National Institutes of Health (NIH) recommends contacting your doctor.

Comparison studies have not shown one skeletal muscle relaxant to be superior to another. Cyclobenzaprine is the most heavily studied and has been shown to be effective for various musculoskeletal conditions. The sedative properties of tizanidine and cyclobenzaprine may benefit patients with insomnia caused by severe muscle spasms.

• Cyclobenzaprine is not designed for long-term use, and patients should follow the regimen provided by their physician, said Dr. Kiran Patel, pain management specialist at Lenox Hill Hospital.
• The slight relaxing feeling can become something that becomes a normal part of their everyday experience.
• Do not take more of it and do not take it more often than your doctor ordered.
• If these effects are mild, they may go away within a few days or a couple of weeks.
• While its exact mechanism of action remains unclear, scientists believe Robaxin can help with pain and discomfort caused by musculoskeletal conditions by blocking the pain signals that are sent to the brain.
• I thought I saw someone standing in my bedroom, and it looked like a child.

Cyclobenzaprine may enhance the effects of other central nervous system depressants, such as alcohol, barbiturates, benzodiazepines and narcotics. According to the DEA, abusers often combine cyclobenzaprine with these depressants to produce or enhance psychoactive effects. Though it is not a controlled substance, the DEA has recorded anecdotal reports of use to induce euphoria and relaxation. Extreme stress can cause increased muscle tension and worsen your current pain or discomfort. Finding new ways to destress and relax can help ease muscle strain while also reducing anxiety and improving your mental health.

The DEA has stated there really is no risk when it comes to Flexeril. In fact, the DEA has not officially listed cyclobenzaprine as a controlled substance at all. However, when abusing Flexeril recreationally, it does become a greater risk to the user. In the first place, Flexeril abuse can end up causing an overdose, the effects of which can be incredibly dangerous. Dangerous fluctuations in body temperature, irregular heartbeat, and even convulsions are all possible from too much cyclobenzaprine recreational use. Flexeril recreational use can also end up leading to the development of physical dependency.

If you experience any of the following symptoms, call your doctor immediately:

Evidence suggests that the net effect of cyclobenzaprine is a reduction of tonic somatic motor activity, influencing both gamma (γ) and alpha (α) motor systems. Acute recovery phase of myocardial infarction, and patients with arrhythmias, heart block or conduction disturbances, or congestive heart failure. In the higher dose groups this microscopic change was seen after 26 weeks and even earlier in rats which died prior to 26 weeks; at lower doses, the change was not seen until after 26 weeks.

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It can occur when Tetracyclic Compounds and MAOIs both raise the level of serotonin too high in the body. It can cause changes in blood pressure, body temperature and lead to a change in behavior. To add to the risk of overdose, addiction, and mixing substances along with cyclobenzaprine recreational use, patients can also be extremely allergic to Flexeril which can cause the body to react quickly. If a person has an overactive thyroid, heart issues or problems with the liver, Flexeril can be risky and should not be taken.

DOSAGE AND ADMINISTRATION

The plasma concentration of cyclobenzaprine is increased in patients with hepatic impairment (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Hepatic Impairment). Pharmacologic similarities among the tricyclic drugs require that certain withdrawal symptoms be considered when FLEXERIL is administered, even though they have not been reported to occur with this drug. Abrupt cessation of treatment after prolonged administration rarely may produce nausea, headache, and malaise. Methocarbamol can be used for long or short-term treatment as advised by a doctor. On the other hand, cyclobenzaprine is generally not prescribed for longer than two or three weeks. Flexeril (generic name cyclobenzaprine) was developed in the 1970s.

Fexmid is a brand name tablet that comes in a 7.5 mg tablet. Amrix is an extended-release capsule that can be taken once daily in a 15 mg – 30 mg dose. Concomitant use of monoamine oxidase (MAO) inhibitors or within 14 days after their discontinuation. Hyperpyretic crisis seizures, and deaths have occurred in patients receiving cyclobenzaprine (or structurally similar tricyclic antidepressants) concomitantly with MAO inhibitor drugs. The plasma concentration of cyclobenzaprine is increased in the elderly (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Elderly). The elderly may also be more at risk for CNS adverse events such as hallucinations and confusion, cardiac events resulting in falls or other sequelae, drug-drug and drug-disease interactions.

If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. Cyclobenzaprine caused slight to moderate increase in heart rate in animals. At oral doses of up to 10 times the human dose, cyclobenzaprine flexeril.live did not adversely affect the reproductive performance or fertility of male or female rats. Cyclobenzaprine did not demonstrate mutagenic activity in the male mouse at dose levels of up to 20 times the human dose.

While its exact mechanism of action remains unclear, scientists believe Robaxin can help with pain and discomfort caused by musculoskeletal conditions by blocking the pain signals that are sent to the brain. It is also believed that Robaxin relaxes the muscle by having depressive effects on the central nervous system. Cyclobenzaprine has not been tested in pediatric patients younger than 15 years of age. The elderly may be at a higher risk for adverse events, including hallucinations and confusion, cardiac events and drug interactions. According to the FDA, the plasma concentration of cyclobenzaprine is increased in the elderly, so the drug should be prescribed only if clearly needed.